
[Completion of the dog toxicity project at the University of Utah: statistical comparison]
Author(s) -
F. W. Bruenger,
R.D. Lloyd
Publication year - 1999
Language(s) - English
Resource type - Reports
DOI - 10.2172/762825
Subject(s) - toxicity , medicine , oncology
Radium (Ra) toxicity in dogs is a cornerstone for the evaluation of plutonium (Pu) toxicity, as it provides a possible link to Pu toxicity in humans. Survival regression models with covariates were used to estimate the risk to survival and the frequency and latency of bone tumor development. It appears for Ra that dose-rate is a more significant contributor to non-survival and bone tumors than is skeletal dose