Open AccessCapillary electrokinetic separations with optical detection. Technical progress report, February 1, 1994--January 31, 1995
Author(s) -
Michael J. Sepaniak
Publication year - 1995
Language(s) - English
Resource type - Reports
DOI - 10.2172/62936
Subject(s) - electrokinetic phenomena , capillary action , capillary electrophoresis , instrumentation (computer programming) , separation (statistics) , micellar electrokinetic chromatography , fullerene , nanotechnology , chromatographic separation , chemistry , chromatography , process engineering , materials science , computer science , engineering , high performance liquid chromatography , organic chemistry , composite material , machine learning , operating system
This multifarious research program is dedicated to the development of capillary electrokinetic separation techniques and associated optical methods of detection. Currently, research is directed at three general objectives. First, fundamental studies of pertinent separation and band broadening mechanisms are being conducted, with the emphasis on achieving rapid separations and understanding separation systems that include highly-ordered assemblies as running buffer additives. Second, instrumentation and methodologies associated with these capillary separation techniques are being advanced. Third, applications of these separation and detection systems should fill current voids in the capabilities of capillary separation techniques. In particular, it should be possible to perform rapid, highly efficient, and selective separations of hydrophobic compounds (e.g., higher MW polycyclic aromatic hydrocarbons (PAHs) and fullerenes), certain optical isomers, DNA fragments, and various pollutants including certain heavy metals