Open AccessTwo-dimensional pixel array image sensor for protein crystallography
Author(s) -
E. Beuville,
J.-F. Beche,
C. Cork
Publication year - 1996
Language(s) - English
Resource type - Reports
DOI - 10.2172/413167
Subject(s) - pixel , monochromatic color , detector , optics , synchrotron , high dynamic range , image sensor , dynamic range , resolution (logic) , physics , image resolution , optoelectronics , materials science , computer science , artificial intelligence
A 2D pixel array image sensor module has been designed for time resolved Protein Crystallography. This smart pixels detector significantly enhances time resolved Laue Protein crystallography by two to three orders of magnitude compared to existing sensors like films or phosphor screens coupled to CCDs. The resolution in time and dynamic range of this type of detector will allow one to study the evolution of structural changes that occur within the protein as a function of time. This detector will also considerably accelerate data collection in static Laue or monochromatic crystallography and make better use of the intense beam delivered by synchrotron light sources. The event driven pixel array detectors, based on the column Architecture, can provide multiparameter information (energy discrimination, time), with sparse and frameless readout without significant dead time. The prototype module consists of a 16x16 pixel diode array bump-bonded to the integrated circuit. The detection area is 150x150 square microns