Effect of radiation on proteins and radiation effects in biochemistry and organic chemistry. Final report, October 15, 1957--October 14, 1974 | Zendy

Bert M. Tolbert | Zendy

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Effect of radiation on proteins and radiation effects in biochemistry and organic chemistry. Final report, October 15, 1957--October 14, 1974

Author(s) -

Bert M. Tolbert

Publication year - 1974

Publication title -

osti oai (u.s. department of energy office of scientific and technical information)

Language(s) - English

Resource type - Reports

DOI - 10.2172/4090103

Subject(s) - lysozyme , irradiation , cataracts , chemistry , biochemistry , amino acid , biology , genetics , physics , nuclear physics

A summary is made of a fifteen year study of chemical effects of radiation of amino acids and proteins. Included is a list of publications: 54 papers, reports and abstracts, and 10 M.S. and Ph.D theses. The report concludes with details of the final two studies done under this contract. These are, first, a study of post-irradiation effects of various gases on gamma irradiated lysozyme. This study showed that H$sub 2$S, O$sub 2$, NO, and N$sub 2$O treatment changed the amount of aggregation products, and also that a certain amount of the irradiated lysozyme was subject to main chain cleavage. The second was a study of proteins in rabbit eye lens cataracts induced by x-irradiation or a high galactose diet. The cataract proteins were more soluble in water than normal proteins, and were present in lower amounts in the eye lens. (auth

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