Ion kinetics and thermodynamics pertinent to mass spectrometric organic speciation. Final report

Essentially all of the completed/in progress studies during the last contract period have involved the NIST HPMS unit. Three distinct areas of in-house research are recognizable: (i) determinations of binding energies and entropies for association and cluster ions, which is accomplished by measuring the temperature dependence of the appropriate equilibrium, (ii) measurement of the temperature dependence unimolecular and bimolecular rate constants, and (iii) evaluation of PA`s, HA`s, and IP`s via measurement of variable-temperature equilibria of the type AH{sup +} + B {longleftrightarrow} BH{sup +} + A, A{sup {minus}} + BH {longleftrightarrow} AH + B{sup {minus}}, and A{sup +} + B {longleftrightarrow} B{sup +} + A. Key results from some representative projects are summarized