Open AccessThe mathematics of virus shell assembly. Progress report 1995--1996
Author(s) -
B. S. Berger
Publication year - 1996
Language(s) - English
Resource type - Reports
DOI - 10.2172/270750
Subject(s) - shell (structure) , folding (dsp implementation) , computer science , core (optical fiber) , engineering , mechanical engineering , telecommunications
This research focuses on applying computational and mathematical techniques to problems in biology, and more specifically to problems in protein folding. Significant progress has been made in the following areas relating to virus shell assembly: the local rules theory has been further developed; development has begun on a second-generation simulator which provides a more physically realistic model of assembly, collaborative efforts have continued with an experimental biologist to verify and inspire the local rules theory; an investigation has been initiated into the mechanics of virus shell assembly; laboratory experiments have been conducted on bacteriophage T4 which verify that the previously believed structure for the core may be incorrect