Open AccessINEL BNCT research program: Annual report, 1995
Author(s) -
J.R. Venhuizen
Publication year - 1996
Language(s) - English
Resource type - Reports
DOI - 10.2172/266747
Subject(s) - neutron capture , medical physics , neutron , radiochemistry , boron , nuclear engineering , linear particle accelerator , nuclear medicine , dosimetry , epithermal neutron , californium , neutron source , nuclear physics , neutron temperature , environmental science , physics , beam (structure) , engineering , medicine , chemistry , optics
This report is a summary of the progress and research produced for the Idaho National Engineering Laboratory (INEL) Boron Neutron Capture Therapy (BNCT) Research Program for calendar year 1995. Contributions from the principal investigators about their individual projects are included, specifically, physics (treatment planning software, real-time neutron beam measurement dosimetry), and radiation biology (large animal models efficacy studies). Design of a reactor based epithermal neutron extraction facility is discussed in detail. Final results of boron magnetic resonance imagining is included for both borocaptate sodium (BSH) and boronophenylalanine (BPA) in rats, and BSH in humans. Design of an epithermal neutron facility using electron linear accelerators is presented, including a treatise on energy removal from the beam target. Information on the multiple fraction injection of BSH in rats is presented