A Systems Biology and Pond Culture-based Understanding and Improvement of Metabolic Processes Related to Productivity in Diverse Microalgal Classes for Viable Biofuel Production | Zendy

Mark Hildebrand | Zendy; Juergen Polle | Zendy; Michael H. Huesemann | Zendy

Open Access

A Systems Biology and Pond Culture-based Understanding and Improvement of Metabolic Processes Related to Productivity in Diverse Microalgal Classes for Viable Biofuel Production

Author(s) -

Mark Hildebrand,

Juergen Polle,

Michael H. Huesemann

Publication year - 2018

Publication title -

osti oai (u.s. department of energy office of scientific and technical information)

Language(s) - English

Resource type - Reports

DOI - 10.2172/1458513

Subject(s) - productivity , biology , biofuel , systems biology , metabolic network , synthetic biology , algae , carbon flux , biochemical engineering , computational biology , topology (electrical circuits) , microbiology and biotechnology , ecology , ecosystem , engineering , macroeconomics , economics , electrical engineering

Microalgal mass culture in open ponds can provide feedstock for biofuels production. However, major gaps exist in the understanding of the effect of metabolic topology on cellular carbon partitioning and its regulation with regards to productivity. Our research develops two emerging platform green algal species for biofuels production as model systems: Acutodesmus (Scenedesmus) obliquus and Coelastrella sp. Our Systems Biology approach includes genomicsbased investigations with climate-simulated pond culturing to identify species specific versus general green algal mechanisms underlying performance in realistic biofuels production scenarios.

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