Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation
Author(s) -
Gerald V. Naccarelli,
W. Frank Peacock
Publication year - 2009
Publication title -
vascular health and risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.892
H-Index - 68
eISSN - 1178-2048
pISSN - 1176-6344
DOI - 10.2147/vhrm.s7616
Subject(s) - medicine , atrial fibrillation , cardiology , heart failure , angiotensin receptor blockers , stroke (engine) , cardiac arrhythmia , renin–angiotensin system , angiotensin ii , receptor , blood pressure , mechanical engineering , engineering
Atrial fibrillation (AF) is the most common form of cardiac arrhythmia and is associated with an increased risk of cardiovascular morbidity and mortality, especially due to ischemic stroke. The occurrence of AF leads to atrial electrical and structural remodeling. The renin-angiotensin system appears to play a role in the development of atrial arrhythmias by its involvement in both of these processes. Large-scale hypertension trials and heart failure trials have indicated the potential value of angiotensin II receptor blockers in the treatment of AF.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom