Hyperhomocysteinemia and vascular access thrombosis in hemodialysis patients: a retrospective study | Zendy

Chadi Saifan | Zendy; El-Charabaty | Zendy; El-Sayegh | Zendy

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Hyperhomocysteinemia and vascular access thrombosis in hemodialysis patients: a retrospective study

Author(s) -

Chadi Saifan,

El-Charabaty,

El-Sayegh

Publication year - 2013

Publication title -

vascular health and risk management

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.892

H-Index - 68

eISSN - 1178-2048

pISSN - 1176-6344

DOI - 10.2147/vhrm.s47255

Subject(s) - medicine , hyperhomocysteinemia , hemodialysis , homocysteine , thrombosis , aspirin , diabetes mellitus , retrospective cohort study , end stage renal disease , dialysis , incidence (geometry) , gastroenterology , kidney disease , surgery , endocrinology , physics , optics

Elevated total plasma homocysteine is an independent risk factor for arterial and venous thrombosis in patients with normal renal function. Patients on hemodialysis have a high prevalence of mild to moderate hyperhomocysteinemia. Conflicting retrospective analyses and prospective studies have been reported regarding the association between total homocysteine levels and hemodialysis vascular thrombosis. The purpose of this retrospective study was to investigate the relationship between hyperhomocysteinemia and vascular access thrombosis (VAT) in patients on hemodialysis.

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