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Efficacy of vildagliptin in combination with insulin in patients with type 2 diabetes and severe renal impairment
Author(s) -
Valentina Lukashevich,
Anja Schweizer,
James E. Foley,
Dickinson,
PerHenrik Groop,
Wolfgang Kothny
Publication year - 2013
Publication title -
vascular health and risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.892
H-Index - 68
eISSN - 1178-2048
pISSN - 1176-6344
DOI - 10.2147/vhrm.s39300
Subject(s) - medicine , vildagliptin , type 2 diabetes , diabetes mellitus , insulin , endocrinology
The purpose of this study was to evaluate the efficacy of vildagliptin 50 mg once daily in patients with severe renal impairment (estimated glomerular filtration rate < 30 mL/min/1.73 m(2)) and longstanding type 2 diabetes not adequately controlled with insulin therapy, which is a difficult-to-treat population, with limited therapeutic options and a high susceptibility to hypoglycemia.

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