The potential benefit of stem cell therapy after stroke: an update
Author(s) -
Soma Banerjee,
Chataway,
Deborah A. Williamson,
Nagy Habib
Publication year - 2012
Publication title -
vascular health and risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.892
H-Index - 68
eISSN - 1178-2048
pISSN - 1176-6344
DOI - 10.2147/vhrm.s25745
Subject(s) - medicine , stroke (engine) , clinical trial , intensive care medicine , stem cell therapy , stem cell , stroke recovery , medline , physical therapy , rehabilitation , pathology , surgery , transplantation , mechanical engineering , engineering , biology , political science , law , genetics
Stroke is a leading cause of death and disability worldwide. Stem cell therapy is an emerging therapeutic modality with evidence of significant benefits in preclinical stroke models. A number of phase I and II clinical trials have now been completed, with several more currently under way. Translation to the bedside, however, remains a long way off, and there are many questions that remain unanswered. This review will summarize the current evidence and ongoing clinical trials worldwide, and explore the challenges to making this a realistic treatment option for the future.
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