Effect of ramipril on renal function in patients with intermittent claudication | Zendy

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Effect of ramipril on renal function in patients with intermittent claudication

Author(s) -

Simon Hobbs

Publication year - 2008

Publication title -

vascular health and risk management

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.892

H-Index - 68

eISSN - 1178-2048

pISSN - 1176-6344

DOI - 10.2147/vhrm.s2340

Subject(s) - medicine , ramipril , renal function , creatinine , intermittent claudication , claudication , renal artery stenosis , ace inhibitor , blood pressure , urology , cardiology , surgery , renal artery , angiotensin converting enzyme , vascular disease , kidney , arterial disease

The Heart Outcomes Prevention Study (HOPE) demonstrated that ramipril resulted in a blood-pressure-independent 25% reduction in cardiovascular events in patients with peripheral arterial disease (PAD). Despite this, general practitioners and vascular surgeons remain reluctant to prescribe ACE inhibitors in this group of patients because of concerns about renal artery stenosis (RAS). We aimed to define the effect of ramipril on renal function in patients with intermittent claudication (IC).

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