Animal-derived surfactants for the treatment and prevention of neonatal respiratory distress syndrome: summary of clinical trials
Author(s) -
Fernando Moya
Publication year - 2009
Publication title -
therapeutics and clinical risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 55
eISSN - 1178-203X
pISSN - 1176-6336
DOI - 10.2147/tcrm.s4029
Subject(s) - medicine , clinical trial , pulmonary surfactant , neonatal respiratory distress syndrome , respiratory distress , intensive care medicine , surgery , biology , gestational age , pregnancy , biochemistry , genetics
Available literature suggests that the advantage of animal-derived surfactants over first-generation synthetic agents derives from the presence of surface-active proteins and their phospholipid content. Here we summarize the results of clinical trials comparing animal-derived surfactant preparations with other animal-derived surfactants and with both first-and second-generation synthetic surfactants.
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