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Fracture risk associated with continuation versus discontinuation of bisphosphonates after 5 years of therapy in patients with primary osteoporosis: a systematic review and meta-analysis
Author(s) -
Lisa-Ann Fraser,
Kelly Vogt,
Rick Adachi,
Lehana Thabane
Publication year - 2011
Publication title -
therapeutics and clinical risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 55
eISSN - 1178-203X
pISSN - 1176-6336
DOI - 10.2147/tcrm.s19385
Subject(s) - medicine , discontinuation , relative risk , osteoporosis , meta analysis , adverse effect , bisphosphonate , confidence interval , randomized controlled trial , number needed to harm , physical therapy , number needed to treat
The risks and benefits of continuing bisphosphonate therapy beyond 5 years in patients with primary osteoporosis have not been well established.

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