Contribution of capecitabine for therapy of patients with gastroesophageal cancer: an update of recent phase III results
Author(s) -
Putao Cen,
Eric D. Tetzlaff,
Jaffer A. Ajani
Publication year - 2008
Publication title -
therapeutics and clinical risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 55
eISSN - 1178-203X
pISSN - 1176-6336
DOI - 10.2147/tcrm.s1446
Subject(s) - capecitabine , medicine , clinical trial , cancer , oncology , fluorouracil , phases of clinical research , colorectal cancer
Capecitabine, an orally administered fluoropyrimidines, is widely used in the treatment of multiple malignancies. It has been extensively evaluated in patients with gastroesophageal carcinoma. Since recent reviews have discussed phase I/II trials (Cancer 107:221-231, 2006; Drugs 67:601-610, 2007), we focus on the impact of the results of the most current phase III trials using capectiabine in the treatment of advanced gastroesophageal cancers, primarily in the first-line setting.
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