Open AccessLong-term management of Alport syndrome in pediatric patients
Author(s) -
Clifford E. Kashtan
Publication year - 2013
Publication title -
pediatric health medicine and therapeutics
Language(s) - English
Resource type - Journals
ISSN - 1179-9927
DOI - 10.2147/phmt.s35667
Subject(s) - alport syndrome , medicine , disease , glomerular basement membrane , kidney disease , type iv collagen , glomerulonephritis , kidney , pediatrics , biology , genetics , laminin , cell
Alport syndrome, an important inherited cause of end-stage renal disease, has long been considered an untreatable disorder. That view is changing as a result of treatment studies in experimental animals and human populations. This review describes current management of Alport kidney disease, which is based on early diagnosis and institution of therapy with antagonists of the renin-angiotensin-aldosterone system.
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