Open AccessCYP2D6 polymorphisms influence the efficacy of adjuvant tamoxifen in Thai breast cancer patients
Author(s) -
Chonlaphat Sukasem,
Ekaphop Sirachainan,
Sureerat Jaruhathai,
Narumol Trachu,
Ravat Panvichian,
T. Sirisinha,
Touch Ativitavas,
Vorachai Ratanatharathorn
Publication year - 2012
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s32160
Subject(s) - medicine , tamoxifen , breast cancer , adjuvant , oncology , cyp2d6 , cancer , gynecology , cytochrome p450 , metabolism
We evaluated single nucleotide polymorphisms (SNPs) of CYP2D6 to identify those that influence the efficiency of tamoxifen in adjuvant treatment of breast cancer through a matched case-control study.
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