Open AccessPIK3CA gene mutation associated with poor prognosis of lung adenocarcinoma
Author(s) -
Wentao Yue,
Lína Zhang,
Lei Shi,
Xiaoting Zhao,
Yue Wang
Publication year - 2013
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s41643
Subject(s) - adenocarcinoma , mutation , lung , medicine , gene , bioinformatics , gene mutation , lung cancer , cancer research , oncology , genetics , biology , cancer
PIK3CA gene mutations have been detected in many malignancies, but the frequency of different mutations and their role in the carcinogenesis of lung adenocarcinoma are still unclear. The purpose of this study was to explore the clinical pathological impact and prognostic implications of PIK3CA mutations in lung adenocarcinoma.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom