&gamma;-H2AX expression detected by immunohistochemistry correlates with prognosis in early operable non-small cell lung cancer | Zendy

Dimitrios Matthaios | Zendy; Foukas | Zendy; Panagiotis Hountis | Zendy; Trypsianis | Zendy; Panayiotides | Zendy; Εkaterini Chatzaki | Zendy; Demosthenes Bouros | Zendy; Karakitsos | Zendy; Kakolyris | Zendy; Maria Kefala | Zendy; Ekaterini Pantelidaki | Zendy

Open Access

γ-H2AX expression detected by immunohistochemistry correlates with prognosis in early operable non-small cell lung cancer

Author(s) -

Dimitrios Matthaios,

Foukas,

Panagiotis Hountis,

Trypsianis,

Panayiotides,

Εkaterini Chatzaki,

Demosthenes Bouros,

Karakitsos,

Kakolyris,

Maria Kefala,

Ekaterini Pantelidaki

Publication year - 2012

Publication title -

oncotargets and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 60

ISSN - 1178-6930

DOI - 10.2147/ott.s36995

Subject(s) - medicine , lung cancer , hazard ratio , proportional hazards model , immunohistochemistry , confidence interval , pneumonectomy , oncology , cohort , lymph node , carcinoma , gastroenterology , pathology

Phosphorylation of the H2AX histone is an early indicator of DNA double-strand breaks and of the resulting DNA damage response. In the present study, we assessed the expression and prognostic significance of γ-H2AX in a cohort of 96 patients with operable non-small cell lung carcinoma.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research