Silencing of Long Non-Coding RNA Colon Cancer-Associated Transcript 2 Inhibits the Growth and Metastasis of Gastric Cancer Through Blocking mTOR Signaling | Zendy

Sen Lin | Zendy; Hongbo Wang | Zendy; Wenjuan Yang | Zendy; Aiguang Wang | Zendy; Chao Geng | Zendy

Open Access

<p>Silencing of Long Non-Coding RNA Colon Cancer-Associated Transcript 2 Inhibits the Growth and Metastasis of Gastric Cancer Through Blocking mTOR Signaling</p>

Author(s) -

Sen Lin,

Hongbo Wang,

Wenjuan Yang,

Aiguang Wang,

Chao Geng

Publication year - 2020

Publication title -

oncotargets and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 60

ISSN - 1178-6930

DOI - 10.2147/ott.s220302

Subject(s) - pi3k/akt/mtor pathway , cancer research , viability assay , cell cycle , transfection , cell growth , gene silencing , autophagy , apoptosis , biology , protein kinase b , microbiology and biotechnology , signal transduction , cell culture , gene , biochemistry , genetics

This study aimed to evaluate the specific role of colon cancer-associated transcript 2 (CCAT2) on gastric cancer (GC), and reveal the potential regulatory mechanism relating to mammalian target of rapamycin (mTOR) signaling.

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