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<p>Silencing circZFR inhibits the proliferation, migration and invasion of human renal carcinoma cells by regulating miR-206</p>
Author(s) -
Mi Wang,
Yisheng Gao,
Jie Liu
Publication year - 2019
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s215012
Subject(s) - gene knockdown , gene silencing , cancer research , viability assay , wnt signaling pathway , cell migration , cell growth , pi3k/akt/mtor pathway , downregulation and upregulation , protein kinase b , renal cell carcinoma , western blot , apoptosis , cell , chemistry , biology , medicine , signal transduction , microbiology and biotechnology , pathology , gene , biochemistry
Renal cell carcinoma (RCC) is the most prevalent kind of kidney cancer. At present, the most efficient treatment mean is surgery. 40% patients with clear cell RCC (ccRCC) relapse after surgery. Identifying novel therapeutic markers and spots for early detection and treatment of RCC is necessary.

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