Long noncoding RNA DLEU1 aggravates glioma progression via the miR-421/MEF2D axis | Zendy

Feng Li | Zendy; Mingyuan He | Zendy; Min Rao | Zendy; Jiandong Diao | Zendy; Yonggang Zhu | Zendy

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Long noncoding RNA DLEU1 aggravates glioma progression via the miR-421/MEF2D axis

Author(s) -

Feng Li,

Mingyuan He,

Min Rao,

Jiandong Diao,

Yonggang Zhu

Publication year - 2019

Publication title -

oncotargets and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 60

ISSN - 1178-6930

DOI - 10.2147/ott.s207542

Subject(s) - gene knockdown , glioma , competing endogenous rna , cancer research , microrna , apoptosis , cell growth , cell culture , downregulation and upregulation , long non coding rna , biology , microbiology and biotechnology , chemistry , gene , genetics

Long noncoding RNA (lncRNA) deleted in lymphocytic leukemia 1 (DLEU1) was reported to be involved in the development and progression of multiple cancers. However, the accurate expression pattern, biological function and potential molecular mechanism of DLEU1 in glioma are not yet known. The present study investigated the role of DLEU in the development and progression of glioma, as well as the potential mechanism played by DLEU1 in glioma.

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