MACC1 promotes angiogenesis in cholangiocarcinoma by upregulating VEGFA | Zendy

Tao Peng | Zendy; Zhonghu Li | Zendy; Dajiang Li | Zendy; Shuguang Wang | Zendy

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<p>MACC1 promotes angiogenesis in cholangiocarcinoma by upregulating VEGFA</p>

Author(s) -

Tao Peng,

Zhonghu Li,

Dajiang Li,

Shuguang Wang

Publication year - 2019

Publication title -

oncotargets and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 60

ISSN - 1178-6930

DOI - 10.2147/ott.s197319

Subject(s) - gene knockdown , angiogenesis , vascular endothelial growth factor a , blot , immunohistochemistry , western blot , cancer research , downregulation and upregulation , metastasis , real time polymerase chain reaction , chemistry , vascular endothelial growth factor , medicine , pathology , vegf receptors , cancer , gene , biochemistry

Angiogenesis actively contributes to tumor growth and metastasis. MACC1 was reported to be associated with tumor progression. In the present study, we aimed to investigate the expression and role of MACC1 in cholangiocarcinoma (CCA) and its correlation with angiogenesis.

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