Long noncoding RNA UCA1 targets miR-582-5p and contributes to the progression and drug resistance of bladder cancer cells through ATG7-mediated autophagy inhibition | Zendy

Junfeng Wu | Zendy; Wei Li | Zendy; Jinzhuo Ning | Zendy; Weimin Yu | Zendy; Ting Rao | Zendy; Fan Cheng | Zendy

Open Access

Long noncoding RNA UCA1 targets miR-582-5p and contributes to the progression and drug resistance of bladder cancer cells through ATG7-mediated autophagy inhibition

Author(s) -

Junfeng Wu,

Wei Li,

Jinzhuo Ning,

Weimin Yu,

Ting Rao,

Fan Cheng

Publication year - 2019

Publication title -

oncotargets and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 60

ISSN - 1178-6930

DOI - 10.2147/ott.s183940

Subject(s) - bladder cancer , gene knockdown , small hairpin rna , autophagy , cancer research , microrna , western blot , downregulation and upregulation , cancer , rna interference , gene silencing , cancer cell , chemistry , medicine , rna , gene , apoptosis , biochemistry

Rently, the incidence of bladder cancer has been on the rise. Accumulating researches have been conducted to clarify the molecular mechanisms and potential therapeutic targets of bladder cancer. The present study aims to explore the regulatory mechanism of the urothelial carcinoma-associated 1 (UCA1)-miR-582-5p-ATG7 axis in bladder cancer.

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