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Long noncoding RNA UCA1 promotes the proliferation, invasion, and migration of nasopharyngeal carcinoma cells via modulation of miR-145
Author(s) -
Jing Wu,
Mingyu Du,
Qian Zhang,
Wenjun Zhang,
Yanxin Fan,
Li Yin,
Qian Fei,
Xuesong Jiang,
Wei Chen,
Huanfeng Zhu,
Pengwei Yan,
Xia He,
Xiuhua Bian
Publication year - 2018
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s182290
Subject(s) - nasopharyngeal carcinoma , carcinogenesis , long non coding rna , cancer research , competing endogenous rna , cell migration , cell growth , oncogene , downregulation and upregulation , biology , cell culture , cell , western blot , microrna , metastasis , gentamicin protection assay , microbiology and biotechnology , cancer , gene , medicine , cell cycle , genetics , radiation therapy
Nasopharyngeal carcinoma (NPC) is a common malignant tumor characterized by highly malignant local invasion and distant metastasis. Recently, increasing attention has been paid to long noncoding RNAs (lncRNAs), which play significant roles in tumorigenesis and progression. However, little is known about the potential role of the lncRNA urothelial carcinoma-associated 1 (UCA1) in NPC cell invasion and migration.

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