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Synergistic suppression effect on tumor growth of acute myeloid leukemia by combining cytarabine with an engineered oncolytic vaccinia virus
Author(s) -
Jiamin Peng,
Shibing Wang,
Weimin Fan,
Shuangshuang Li,
Yi Wu,
Xiaozhou Mou,
Jianchao Wang,
Xiangmin Tong
Publication year - 2018
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s172037
Subject(s) - cytarabine , myeloid leukemia , oncolytic virus , leukemia , in vivo , cancer research , apoptosis , immunology , medicine , pharmacology , biology , tumor cells , biochemistry , microbiology and biotechnology
In consideration of the drug resistance and side effects associated with cytarabine, one of the most effective drugs for the treatment of acute myeloid leukemia (AML), there is a need for safer and effective strategies.

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