Open AccessmiR-141-3p is a key negative regulator of the EGFR pathway in osteosarcoma
Author(s) -
Jiashi Wang,
Guangbin Wang,
Bin Li,
Chuang Qiu,
Ming He
Publication year - 2018
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s171304
Subject(s) - osteosarcoma , western blot , cell growth , microrna , cancer research , apoptosis , immunohistochemistry , transfection , biology , microbiology and biotechnology , cell culture , gene , immunology , biochemistry , genetics
Many studies have used miRNA to modulate osteosarcoma development by regulating protein expression, and these studies showed that the expression of EGFR is increased in osteosarcoma.
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