Long noncoding RNA Sox2 overlapping transcript (SOX2OT) promotes non-small-cell lung cancer migration and invasion via sponging microRNA 132 (miR-132) | Zendy

Kewei Zhang | Zendy; Yang Li | Zendy; Limei Qu | Zendy; Xiaobo Ma | Zendy; Hongguang Zhao | Zendy; Ying Tang | Zendy

Open Access

Long noncoding RNA Sox2 overlapping transcript (SOX2OT) promotes non-small-cell lung cancer migration and invasion via sponging microRNA 132 (miR-132)

Author(s) -

Kewei Zhang,

Yang Li,

Limei Qu,

Xiaobo Ma,

Hongguang Zhao,

Ying Tang

Publication year - 2018

Publication title -

oncotargets and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 60

ISSN - 1178-6930

DOI - 10.2147/ott.s168654

Subject(s) - long non coding rna , microrna , gene knockdown , downregulation and upregulation , cell growth , biology , cancer research , sox2 , oncogene , cell , microbiology and biotechnology , cell culture , gene , transcription factor , cell cycle , genetics

Long noncoding RNA (lncRNA) Sox2 overlapping transcript (SOX2OT) has been reported to be upregulated in various types of cancers, including non-small-cell lung cancer (NSCLC). However, the biological role and underlying mechanism of SOX2OT activity in NSCLC remain largely unknown. This study aims to investigate the function and possible molecular mechanisms of SOX2OT in NSCLC.

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