Expression of organic anion-transporting polypeptides 1B3, 1B1, and 1A2 in human pancreatic cancer reveals a new class of potential therapeutic targets | Zendy

Evangelos Briasoulis | Zendy; Valentinos Kounnis | Zendy; Loakim | Zendy; Martin Svoboda | Zendy; Andreas G. Tzakos | Zendy; Ioannis Sainis | Zendy; T. Thalhammer | Zendy; Georg Steiner | Zendy

Open Access

Expression of organic anion-transporting polypeptides 1B3, 1B1, and 1A2 in human pancreatic cancer reveals a new class of potential therapeutic targets

Author(s) -

Evangelos Briasoulis,

Valentinos Kounnis,

Loakim,

Martin Svoboda,

Andreas G. Tzakos,

Ioannis Sainis,

T. Thalhammer,

Georg Steiner

Publication year - 2011

Publication title -

oncotargets and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 60

ISSN - 1178-6930

DOI - 10.2147/ott.s16706

Subject(s) - cancer research , class (philosophy) , pancreatic cancer , chemistry , pharmacology , medicine , computational biology , cancer , biology , computer science , artificial intelligence

Organic anion-transporting polypeptides (OATPs) are influx transporters that mediate intracellular uptake of selective endogenous and xenobiotic compounds. Identification of new molecular targets and discovery of novel targeted therapies is top priority for pancreatic cancer, which lacks any effective therapy.

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