Open AccessmiR-488 inhibits cell growth and metastasis in renal cell carcinoma by targeting HMGN5
Author(s) -
Xin Wei,
Lili Yu,
Xiangbo Kong
Publication year - 2018
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s156361
Subject(s) - renal cell carcinoma , cancer research , metastasis , cell growth , oncology , medicine , cell , biology , cancer , genetics
microRNAs are thought to play crucial roles in tumorigenesis. Dysregulation of miR-488 has been implicated to be involved in several cancer progressions. However, the biological functions of miR-488 in renal cell carcinoma (RCC) remain unclear. This study aimed to explore the molecular mechanism underlying the role of miR-488 in RCC development.
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