Kanglaite reverses multidrug resistance of HCC by inducing apoptosis and cell cycle arrest via PI3K/AKT pathway | Zendy

Chendong Yang | Zendy; Aihua Hou | Zendy; Chunfeng Yu | Zendy; Lingling Dai | Zendy; Wen Wang | Zendy; Kangle Zhang | Zendy; Hongmin Shao | Zendy; Jinghua Ma | Zendy; Xu Wenjuan | Zendy

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Kanglaite reverses multidrug resistance of HCC by inducing apoptosis and cell cycle arrest via PI3K/AKT pathway

Author(s) -

Chendong Yang,

Aihua Hou,

Chunfeng Yu,

Lingling Dai,

Wen Wang,

Kangle Zhang,

Hongmin Shao,

Jinghua Ma,

Xu Wenjuan

Publication year - 2018

Publication title -

oncotargets and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 60

ISSN - 1178-6930

DOI - 10.2147/ott.s153814

Subject(s) - pi3k/akt/mtor pathway , apoptosis , protein kinase b , cell cycle checkpoint , cancer research , medicine , multiple drug resistance , cell cycle , pharmacology , chemistry , biochemistry , antibiotics

Multidrug resistance (MDR) frequently contributes to the failure of chemotherapeutic treatments in patients diagnosed with hepatocellular carcinoma (HCC). Revealing the molecular mechanism of MDR is indispensable for the development of effective chemotherapeutic drugs.

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