MicroRNA-381 enhances radiosensitivity in esophageal squamous cell carcinoma by targeting X-linked inhibitor of apoptosis protein
Author(s) -
Suna Zhou,
Yaoyou Cui,
DeQuan Yu,
Jun Liang,
Mingxin Zhang,
Ye Wenguang
Publication year - 2017
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s134551
Subject(s) - xiap , radioresistance , microrna , apoptosis , radiosensitivity , cancer research , gene silencing , ectopic expression , inhibitor of apoptosis , cell growth , flow cytometry , cell culture , microbiology and biotechnology , chemistry , biology , programmed cell death , medicine , radiation therapy , caspase , gene , biochemistry , genetics
Increasing evidence indicates that radioresistance remains a major problem in the treatment of patients with esophageal squamous cell carcinoma (ESCC). This study was designed to investigate the expression of microRNA-381 (miR-381) and its function in the radioresistance of ESCC.
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