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Diabetic and non-diabetic human cornea and tear γ-glutamyl transpeptidase activity
Author(s) -
Marlyn P. Langford,
Liang Liang,
Redens,
Sushil K. Jain,
Samantha Burnham,
Sakhalkar
Publication year - 2013
Publication title -
clinical ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 56
eISSN - 1177-5483
pISSN - 1177-5467
DOI - 10.2147/opth.s37546
Subject(s) - medicine , diabetes mellitus , cornea , tears , oxidative stress , ophthalmology , endocrinology , surgery
Diabetes-related eye disease is due in part to oxidative stress. Gamma-glutamyl transpeptidase (GGT) is a γ-glutamyl cycle enzyme that protects against oxidative stress via glutathione recapture. This study investigates corneal and Schirmer tears GGT activity in diabetic and non-diabetic adults aged 50 to 83 years old.

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