Open AccessEfficacy of various antioxidants in the protection of the retinal pigment epithelium from oxidative stress
Author(s) -
Cindy Hutnik,
Dov B. Kagan,
Hong Liu
Publication year - 2012
Publication title -
clinical ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 56
eISSN - 1177-5483
pISSN - 1177-5467
DOI - 10.2147/opth.s35139
Subject(s) - oxidative stress , retinal pigment epithelium , medicine , ophthalmology , retinal , antioxidant , pigment , pharmacology , biology , biochemistry , chemistry , organic chemistry
Oxidative stress induced retinal pigment epithelium (RPE) dysfunction is hypothesized to be fundamental in the pathogenesis of age-related macular degeneration (AMD). This study investigated whether vitamin C, vitamin C phosphate, vitamin E, propofol, betaxolol, and N-acetyl cysteine (NAC) protect human RPE cells from oxidative stress.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom