Major single nucleotide polymorphisms in polypoidal choroidal vasculopathy: a comparative analysis between Thai and other Asian populations | Zendy

Chantaren Patchima | Zendy; Ruamviboonsuk | Zendy; Ponglikitmongkol | Zendy; Tiensuwan | Zendy; Engkagul | Zendy; Promso Somying | Zendy

Open Access

Major single nucleotide polymorphisms in polypoidal choroidal vasculopathy: a comparative analysis between Thai and other Asian populations

Author(s) -

Chantaren Patchima,

Ruamviboonsuk,

Ponglikitmongkol,

Tiensuwan,

Engkagul,

Promso Somying

Publication year - 2012

Publication title -

clinical ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.025

H-Index - 56

eISSN - 1177-5483

pISSN - 1177-5467

DOI - 10.2147/opth.s30529

Subject(s) - macular degeneration , genotype , single nucleotide polymorphism , factor h , medicine , allele , polymorphism (computer science) , genetics , allele frequency , biology , ophthalmology , gene , antibody , complement system

To investigate the association in a Thai population between the major age-related macular degeneration (AMD) susceptibility loci, Y402H and I62V in the complement factor H (CFH) and A69S in the age-related maculopathy susceptibility 2 (ARMS2) genes, and polypoidal choroidal vasculopathy (PCV).

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