Retinoblastoma treatment: impact of the glycolytic inhibitor 2-deoxy-d-glucose on molecular genomics expression in LHBETATAG retinal tumors | Zendy

Timothy G. Murray | Zendy; Pina | Zendy; Samuel Samuel Houston | Zendy; Tulay KoruSengul | Zendy; Decatur | Zendy; Lubov Nathanson | Zendy; Jennifer Clarke | Zendy; Lampidis | Zendy

Open Access

Retinoblastoma treatment: impact of the glycolytic inhibitor 2-deoxy-d-glucose on molecular genomics expression in LHBETATAG retinal tumors

Author(s) -

Timothy G. Murray,

Pina,

Samuel Samuel Houston,

Tulay KoruSengul,

Decatur,

Lubov Nathanson,

Jennifer Clarke,

Lampidis

Publication year - 2012

Publication title -

clinical ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.025

H-Index - 56

eISSN - 1177-5483

pISSN - 1177-5467

DOI - 10.2147/opth.s29688

Subject(s) - retinoblastoma , retinal , warburg effect , medicine , apoptosis , microbiology and biotechnology , biology , glycolysis , cancer research , gene , cancer , pathology , ophthalmology , genetics , cancer cell , metabolism

The purpose of this study was to evaluate the effect of 2-deoxy-D-glucose (2-DG) on the spatial distribution of the genetic expression of key elements involved in angiogenesis, hypoxia, cellular metabolism, and apoptosis in LH(BETA)T(AG) retinal tumors.

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