Potential role of intravitreal human placental stem cell implants in inhibiting progression of diabetic retinopathy in type 2 diabetes: neuroprotective growth factors in the vitreous | Zendy

Sergio Zaccaria Scalinci | Zendy; L. Scorolli | Zendy; Giulia Corradetti | Zendy; Domanico | Zendy; Enzo Maria Vingolo | Zendy; Bifani | Zendy; Siravo | Zendy

Open Access

Potential role of intravitreal human placental stem cell implants in inhibiting progression of diabetic retinopathy in type 2 diabetes: neuroprotective growth factors in the vitreous

Author(s) -

Sergio Zaccaria Scalinci,

L. Scorolli,

Giulia Corradetti,

Domanico,

Enzo Maria Vingolo,

Bifani,

Siravo

Publication year - 2011

Publication title -

clinical ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.025

H-Index - 56

eISSN - 1177-5483

pISSN - 1177-5467

DOI - 10.2147/opth.s21161

Subject(s) - medicine , diabetic retinopathy , mesenchymal stem cell , neuroprotection , stem cell therapy , ophthalmology , stem cell , neurotrophic factors , vitrectomy , diabetes mellitus , endocrinology , visual acuity , pathology , biology , microbiology and biotechnology , receptor

Intravitreal injection of human mesenchymal stem cells has been shown to be effective in slowing the progression of diabetic retinopathy in an animal model of chemically induced diabetes mellitus. We studied changes in growth factor levels released from human mesenchymal stem cells in the vitreous cavity as well as changes in growth factor levels in host retinal neurons following intravitreal injection.

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