Measurement of bone turnover in prostate cancer patients receiving intermittent androgen suppression therapy
Author(s) -
Hamilton
Publication year - 2010
Publication title -
open access journal of urology
Language(s) - English
Resource type - Journals
ISSN - 1179-1551
DOI - 10.2147/oaju.s13046
Subject(s) - prostate cancer , medicine , n terminal telopeptide , bone remodeling , endocrinology , testosterone (patch) , urology , bone mineral , prostate specific antigen , prostate , androgen deprivation therapy , osteoporosis , cancer , androgen , hormone , osteocalcin , chemistry , alkaline phosphatase , biochemistry , enzyme
Reports on clinical measurements of bone mineral density (BMD) in prostate cancer patients undergoing intermittent androgen suppression therapy (IAS) that allows for hormonal recovery between treatment cycles indicate decreased osteoporosis compared to continuous androgen suppression therapy (CAS). In the present study the effect of IAS on bone metabolism by determinations of CrossLaps, a biochemical marker of collagen degradation, were examined.
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