Higher FKBP5, COMT, CHRNA5, and CRHR1 allele burdens are associated with PTSD and interact with trauma exposure: implications for neuropsychiatric research and treatment
Author(s) -
Joseph A. Boscarino,
Erlich,
Hoffman,
Xiaopeng Zhang
Publication year - 2012
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s29508
Subject(s) - medicine , allele , odds ratio , single nucleotide polymorphism , logistic regression , psychiatry , genetics , genotype , gene , biology
The study aim was to assess the cumulative burden of polymorphisms located within four genetic loci previously associated with posttraumatic stress disorder (PTSD) among outpatients at risk for PTSD.
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