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Our study is the first to report improvement in verbal memory in persons afflicted by FEP who are -ε4 carriers and replicates the prominent verbal memory deficits present in FEP. Our work provides further evidence pointing to an antagonistic pleiotropic effect of -ε4 in neuropsychiatric disorders. Our results merit further research into antagonistic pleiotropic effects in schizophrenia.

Verbal memory improvement in first-episode psychosis <em>APOE-</em>&epsilon;4 carriers: a pleiotropic effect?

Verbal memory improvement in first-episode psychosis <em>APOE-</em>ε4 carriers: a pleiotropic effect?