Micro- and nanotechnology in cell separation | Zendy

Milica Radisic | Zendy; R. Iyer | Zendy; Shashi K. Murthy | Zendy

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Micro- and nanotechnology in cell separation

Author(s) -

Milica Radisic,

R. Iyer,

Shashi K. Murthy

Publication year - 2006

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/nano.2006.1.1.3

Subject(s) - nanotechnology , software portability , context (archaeology) , emerging technologies , computer science , separation (statistics) , biochemical engineering , materials science , engineering , paleontology , machine learning , biology , programming language

This review describes recent work in cell separation using micro- and nanoscale technologies. These devices offer several advantages over conventional, macroscale separation systems in terms of sample volumes, low cost, portability, and potential for integration with other analytical techniques. More importantly, and in the context of modern medicine, these technologies provide tools for point-of-care diagnostics, drug discovery, and chemical or biological agent detection. This review describes work in five broad categories of cell separation based on (1) size, (2) magnetic attraction, (3) fluorescence, (4) adhesion to surfaces, and (5) new emerging technologies. The examples in each category were selected to illustrate separation principles and technical solutions as well as challenges facing this rapidly emerging field.

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