Oral Spirulina Platensis Attenuates Hyperglycemia and Exhibits Antinociceptive Effect in Streptozotocin-Induced Diabetic Neuropathy Rat Model | Zendy

Mohamed M. AbdelDaim | Zendy; M. Shaaban Ali | Zendy; Fedekar F. Madkour | Zendy; Hamed Elgendy | Zendy

Open Access

<p>Oral Spirulina Platensis Attenuates Hyperglycemia and Exhibits Antinociceptive Effect in Streptozotocin-Induced Diabetic Neuropathy Rat Model</p>

Author(s) -

Mohamed M. AbdelDaim,

M. Shaaban Ali,

Fedekar F. Madkour,

Hamed Elgendy

Publication year - 2020

Publication title -

journal of pain research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.888

H-Index - 49

ISSN - 1178-7090

DOI - 10.2147/jpr.s267347

Subject(s) - medicine , spirulina (dietary supplement) , streptozotocin , diabetic neuropathy , nociception , pharmacology , diabetes mellitus , traditional medicine , endocrinology , receptor , raw material , chemistry , organic chemistry

Diabetic neuropathy is a common consequence of diabetes. Hyperalgesia is one of the main symptoms of diabetic neuropathy. In response to noxious stimuli, streptozotocin (STZ)-induced diabetic rats show exaggerated hyperalgesic behavior, while Spirulina platensis has anti-inflammatory, antioxidant, and insulin-like effects. To assess the antinociceptive effect of oral Spirulina platensis (SP) powder on formalin-induced nociceptive responses in STZ-induced diabetic rats.

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