Are dopamine-related genotypes risk factors for excessive gestational weight gain? | Zendy

Gary S. Goldfield | Zendy; Dowler | Zendy; Walker | Zendy; David Cameron | Zendy; Ferraro | Zendy; Doucet | Zendy; Kristi B. Adamo | Zendy

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Are dopamine-related genotypes risk factors for excessive gestational weight gain?

Author(s) -

Gary S. Goldfield,

Dowler,

Walker,

David Cameron,

Ferraro,

Doucet,

Kristi B. Adamo

Publication year - 2013

Publication title -

international journal of women s health

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.136

H-Index - 45

ISSN - 1179-1411

DOI - 10.2147/ijwh.s43935

Subject(s) - weight gain , body mass index , endocrinology , medicine , genotype , birth weight , gestation , biology , pregnancy , genetics , body weight , gene

Excessive gestational weight gain is associated with postpartum weight retention and downstream child obesity. Dopamine plays a critical role in the regulation of energy intake and body weight. The purpose of this study was to examine the relationship between excessive gestational weight gain and dopamine pathway-related polymorphisms, namely the variable nucleotide tandem repeat in the 3'untranslated region (UTR) region of the SLC6A3 (DAT-1) dopamine transporter gene and the 30-base pair variable nucleotide tandem repeat polymorphism of the 5'UTR of the monoamine oxidase-A (MAO-A) gene.

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