Relationship between platelet count and hemodialysis membranes | Zendy

Chadi Saifan | Zendy; Nasr | Zendy; Iskandar Barakat | Zendy; Azzi | Zendy; Marc Saad | Zendy; El-Sayegh | Zendy; Naboush | Zendy

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Relationship between platelet count and hemodialysis membranes

Author(s) -

Chadi Saifan,

Nasr,

Iskandar Barakat,

Azzi,

Marc Saad,

El-Sayegh,

Naboush

Publication year - 2013

Publication title -

international journal of nephrology and renovascular disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.846

H-Index - 27

ISSN - 1178-7058

DOI - 10.2147/ijnrd.s46440

Subject(s) - medicine , platelet , hemodialysis , membrane , dialysis , dialysis tubing , leukocytosis , platelet activation , surgery , chemistry , biochemistry

One factor associated with poor outcomes in hemodialysis patients is exposure to a foreign membrane. Older membranes are very bioincompatible and increase complement activation, cause leukocytosis by activating circulating factors, which sequesters leukocytes in the lungs, and activates platelets. Recently, newer membranes have been developed that were designed to be more biocompatible. We tested if the different "optiflux" hemodialysis membranes had different effects on platelet levels.

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