Active renin mass concentration to determine aldosterone-to-renin ratio in screening for primary aldosteronism
Author(s) -
Marcel Lebel,
Corbin,
Pierre Douville
Publication year - 2011
Publication title -
international journal of nephrology and renovascular disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 27
ISSN - 1178-7058
DOI - 10.2147/ijnrd.s22245
Subject(s) - primary aldosteronism , medicine , renin–angiotensin system , aldosterone , plasma renin activity , hyperaldosteronism , endocrinology , urology , blood pressure
Active renin mass concentration (ARC) is independent of the endogenous level of angiotensinogen, and less variable and more reproducible than plasma renin activity. Reference values for the aldosterone-to-renin ratio (ARR) using ARC are still undefined. The objective of the present study was to determine the threshold of ARR using ARC measurement to screen for primary aldosteronism.
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