Iron oxide nanoparticles and magnetic field exposure promote functional recovery by attenuating free radical-induced damage in rats with spinal cord transection | Zendy

Suman Jain | Zendy; Ajay Pal | Zendy; Singh | Zendy; Tapas Chandra Nag | Zendy; Chattopadhyay | Zendy; Mathur | Zendy

Open Access

Iron oxide nanoparticles and magnetic field exposure promote functional recovery by attenuating free radical-induced damage in rats with spinal cord transection

Author(s) -

Suman Jain,

Ajay Pal,

Singh,

Tapas Chandra Nag,

Chattopadhyay,

Mathur

Publication year - 2013

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s44238

Subject(s) - oxidative stress , iron oxide nanoparticles , spinal cord , spinal cord injury , in vivo , axon , reactive oxygen species , lesion , pharmacology , biophysics , chemistry , in vitro , medicine , biomedical engineering , nanoparticle , materials science , pathology , anatomy , nanotechnology , biochemistry , biology , microbiology and biotechnology , psychiatry

Iron oxide nanoparticles (IONPs) can attenuate oxidative stress in a neutral pH environment in vitro. In combination with an external electromagnetic field, they can also facilitate axon regeneration. The present study demonstrates the in vivo potential of IONPs to recover functional deficits in rats with complete spinal cord injury.

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