Physiologic load-bearing characteristics of autografts, allografts, and polymer-based scaffolds in a critical sized segmental defect of long bone: an experimental study | Zendy

Louis F. Amorosa | Zendy; Jin Lee | Zendy; Aydemir | Zendy; Nizami | Zendy; Hsu - | Zendy; Valbhi Patel | Zendy; Thomas A. Gardner | Zendy; Navalgund | Zendy; DoGyoon Kim | Zendy; S. Park | Zendy; Mao Mao | Zendy; Francis Y. Lee | Zendy

Open Access

Physiologic load-bearing characteristics of autografts, allografts, and polymer-based scaffolds in a critical sized segmental defect of long bone: an experimental study

Author(s) -

Louis F. Amorosa,

Jin Lee,

Aydemir,

Nizami,

Hsu -,

Valbhi Patel,

Thomas A. Gardner,

Navalgund,

DoGyoon Kim,

S. Park,

Mao Mao,

Francis Y. Lee

Publication year - 2013

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s42855

Subject(s) - scaffold , mesenchymal stem cell , biomedical engineering , materials science , stiffness , tissue engineering , medicine , pathology , composite material

To address the challenge of treating critical sized intercalary defects, we hypothesized that under physiologic cyclic loading, autografts, allografts, and scaffolds loaded with and without human mesenchymal stem cells (hMSCs) would have different biomechanical characteristics.

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