Green synthesis of graphene and its cytotoxic effects in human breast cancer cells
Author(s) -
Sangiliyandi Gurunathan,
Jae Woong Han,
Vasuki Eppakayala,
JinHoi Kim
Publication year - 2013
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s42047
Subject(s) - graphene , materials science , biocompatibility , nanotechnology , raman spectroscopy , oxide , chemical engineering , nuclear chemistry , chemistry , physics , engineering , optics , metallurgy
This paper describes an environmentally friendly ("green") approach for the synthesis of soluble graphene using Bacillus marisflavi biomass as a reducing and stabilizing agent under mild conditions in aqueous solution. In addition, the study reported here investigated the cytotoxicity effects of graphene oxide (GO) and bacterially reduced graphene oxide (B-rGO) on the inhibition of cell viability, reactive oxygen species (ROS) generation, and membrane integrity in human breast cancer cells.
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