Preparation and evaluation of SiO2-deposited stearic acid-g-chitosan nanoparticles for doxorubicin delivery
Author(s) -
Hong Yuan,
Anming Bao,
YongZhong Du,
You,
Fuqiang Hu
Publication year - 2012
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s35575
Subject(s) - nanoparticle , stearic acid , materials science , chitosan , micelle , mesoporous material , copolymer , mesoporous silica , nuclear chemistry , zeta potential , chemical engineering , small angle x ray scattering , particle size , drug delivery , nanotechnology , organic chemistry , polymer , chemistry , aqueous solution , scattering , composite material , physics , optics , engineering , catalysis
Both polymer micelles and mesoporous silica nanoparticles have been widely researched as vectors for small molecular insoluble drugs. To combine the advantages of copolymers and silica, studies on the preparation of copolymer-silica composites and cellular evaluation were carried out.
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